Megakaryocytic emperipolesis: A histological finding in myelodysplastic syndrome
نویسندگان
چکیده
منابع مشابه
Megakaryocytic Emperipolesis Associated with Thrombocytopenia: Causative or Coincidence?
Phagocytosis, emperipolesis, and entosis are physiological and pathological phenomena characterized by the engulfment of one cell into another cell [1]. Emperipolesis is defined as active penetration of one cell by another, which remains intact [2]. Emperipolesis differs from phagocytosis in that an engulfed cell exists temporarily within another cell and with an intact normal structure, while ...
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myelodysplastic syndromes (mds) are a group of hematological disorders ranging from chronic refractory anemia to leukemia. there are some reports about association of mds with autoimmune disorders and vasculitis. in this study we describe a patient with mds and vasculitis presenting with central nervous system (cns) involvement. a clinical response to immunosuppressive therapy was also observed...
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The last decade has witnessed a multistep evolution in the understanding of the natural history, clinical manifestations, and some of the molecular mechanisms that underlie the ineffective hematopoiesis and leukemic transformation in the myelodysplastic syndrome (MDS). The international prognostic scoring system, FAB, and WHO classifications have helped define specific subgroups with their char...
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The hallmark of neoplastic disease, including myelodysplastic syndrome (MDS), is clonal proliferation of cells. Clonal proliferation is the consequence of acquired somatic mutation that confers a proliferative advantage to cells. For the myelodysplastic syndrome, the ability to identify clonally derived cells has provided valuable information about the molecular pathogenesis of the disease, the...
متن کاملMyelodysplastic syndrome.
During the past 15 years, important progress has been made in the understanding of the biology and prognosis of myelodysplastic syndrome (MDS). MDS is a clonal disorder characterized by ineffective hematopoiesis, which can lead to either fatal cytopenias or acute myelogenous leukemia (AML). Risk-adapted treatment strategies were established because of the high median age (60-75 years) of the MD...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2009
ISSN: 0377-4929
DOI: 10.4103/0377-4929.56153